Pentobarbital will decrease the extent or influence of lumefantrine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Coadministration with robust CYP3A4 inducers can lead to lowered serum concentrations and lack of antimalarial efficacy pentobarbital will reduce the level or influence of bortezomib by influencing hepatic/intestinal enzyme CYP3A4 metabolism.... https://travisjdtmc.affiliatblogger.com/83207218/the-ultimate-guide-to-is-nembutal-a-cns-depressant