Lousy/Substantial Metabolizers, CYP2D6 The formation of the active metabolite, M1, is mediated by CYP2D6, a polymorphic enzyme. Somewhere around 7% of your populace has lessened activity from the CYP2D6 isoenzyme of cytochrome P450 metabolizing enzyme technique. These folks are “inadequate metabolizers” of debrisoquine, dextromethorphan and tricyclic antidepressants, among the other https://nathanielk763wsg1.blogthisbiz.com/profile